U聽of聽A researcher to work with Northwest Territories communities to promote HPV vaccination, improve COVID-19 vaccination experience

Five-year project to develop culturally appropriate program is among 19 U of A projects to receive new funding from Canadian Institutes of Health Research.

210312-2017_sharma_sangita-0503-main-16x9-3600px.jpg

U of A researcher Sangita Sharma is leading a project working with communities in the Northwest Territories to co-create a culturally appropriate program encouraging more people to get vaccinated against HPV. The team will also gauge people's attitudes and experiences related to COVID-19 vaccines. (Photo: Faculty of Medicine & Dentistry)

A 黑料不打烊 researcher will consult with two Indigenous communities in the Northwest Territories to co-create a culturally appropriate promotion program for the .

HPV is the most common sexually transmitted infection and the main cause of cervical cancer worldwide, but it is preventable with a vaccine for females aged nine to 45 years and males aged nine to 26. The compared with up to 92 per cent in other parts of the country. 

“We’re aiming to develop a community-based program that addresses the communities’ concerns for HPV and ultimately reduces HPV-related cancers,” said Sangita Sharma, 黑料不打烊 Centennial Professor in the Faculty of Medicine & Dentistry and lead of the . 

The (CIHR) that Sharma and her partners have been granted $2.1 million to investigate and improve the utilization of HPV vaccination. The initiative is one of 19 U of A projects receiving a total of $13.7 million in funding from CIHR.

The team will also capture experiences with the COVID-19 vaccine and examine attitudes toward COVID-19 vaccination. The Northwest Territories government is currently offering the to anyone over the age of 18.

Tapping into the wisdom of the community

The project team will work with one small, remote community and another medium-sized, semi-remote community. Community conversations will include Inuvialuit, First Nations and Métis peoples. The project will take five years and will be guided by community advisory boards that include Indigenous community members, leaders and Elders.

“We’re hoping our consultations will take place through on-the-land activities such as fishing, hunting, beading and hide tanning—while the youth are learning from grandparents and parents, from the Elders, so we get the whole community’s perspective,” said Sharma, who also holds the 黑料不打烊 Health Services Chair in Indigenous Health.

The team will use an approach to research known as “Two-Eyed Seeing,” which Sharma explained incorporates the strengths of Indigenous knowledge, wisdom and ways of knowing with the strengths of western knowledge and ways of knowing.

This project builds on Sharma’s on attitudes toward cancer and cancer screening in Indigenous communities, which led to the development of a . 

Sharma’s partners on the project include the two northern communities, the community advisory boards, the research unit and , as well as Fariba Kolahdooz, executive director of U of A’s Indigenous and Global Health Research Group; Gina Ogilvie and Carolyn Gotay of the University of British Columbia; and Donna Kurtz of UBC Okanagan. 

Other U of A projects receiving CIHR funding

,
Faculty of Medicine & Dentistry

Enabling liver cryopreservation by controlling ice recrystallization with small molecule inhibitors

$600,524
, ,
Faculty of Rehabilitation Medicine

Preoperative e-health to prepare for elective total joint replacement surgery: The Prep@Home randomized feasibility trial

$100,000
,
Faculty of Science

Brain cell volume reduction in animal models and people with intracerebral hemorrhagic stroke

$807,075
, ,
Faculty of Nursing

How missed care occurs in nursing homes: A qualitative study of care aides’ perspectives

$100,000
,
Faculty of Medicine & Dentistry

Deciphering immune responses in COVID-19 patients to identify immune correlates of protection and susceptibility for targeted therapeutics

$1,071,000
, ,
Faculty of Nursing

The impact of the COVID-19 pandemic on long-term care home staff and residents

$756,890
,
Faculty of Nursing

Experiences of care aides in long-term care with residents having psychological trauma

$195,076
,
Faculty of Rehabilitation Medicine

Role of inflammation in recovery after spinal cord injury

$956,250
,
Faculty of Agricultural, Life and Environmental Sciences

Dietary ethanolamine and phosphoethanolamine phosphorylase as novel modulators of liver health

$100,000
,
Faculty of Agricultural, Life and Environmental Sciences 

Feeding EPA and DHA to improve clinical symptoms associated with COVID-19 infection

$344,250
,
Faculty of Medicine & Dentistry

Repair in transplant vasculopathy

$807,075
,
Faculty of Medicine & Dentistry

Spinal neuromodulation for restoring function after neural injury or disease

$1,162,800
,
Faculty of Medicine & Dentistry

Pathogenesis of COVID-19 mediated cardiovascular complications: Therapeutic applications

$875,925
,
Faculty of Medicine & Dentistry

The role of glycosphingolipids in the secretion and clearance of extracellular vesicles in brain health and disease

$1,040,400
,
Faculty of Engineering

Synthetic biomaterials to package and deliver siRNA nanoparticles in order to curb uncontrolled growth of leukemic cells

$757,350
,
Faculty of Medicine & Dentistry

Proteinase-activated receptor-2 agonists for mucosal vaccination

$998,325
,
Faculty of Medicine & Dentistry

Development of antisense oligonucleotide-based therapy for facioscapulohumeral muscular dystrophy

$865,800